Disclosure: this post contains affiliate links. If you buy through them, we may earn a commission at no extra cost to you. Prices, availability and policies were checked on Quicksilver Scientific’s website in October 2026 and can change. This article is for general information only and is not medical advice. Talk to your doctor or another qualified healthcare provider before starting any supplement, especially if you’re pregnant, breastfeeding, managing a health condition or taking medication.
Walk down the supplement aisle of any store and you’ll see the same thing on almost every shelf: capsules, tablets and gummies, all promising to support something. What you’ll see far less often is a small glass bottle with a pump, filled with a liquid you hold in your mouth for a minute before swallowing. That’s the world of liposomal supplements, and one of the best-known names in it is Quicksilver Scientific.
Quicksilver Scientific has built a following among integrative and functional medicine practitioners, wellness enthusiasts and biohackers, largely on the strength of its delivery technology. Its products are designed around tiny lipid-based particles that the company says improve absorption compared with conventional forms.
In this guide, we’ll look at who Quicksilver Scientific is, what liposomal and nanoemulsion delivery actually means, how to take these products, a closer look at three of its best-known supplements, what you’ll pay, and the policies worth knowing before you order. We’ll also be clear about what the science does and doesn’t tell us, so you can make an informed decision.
Explore Quicksilver Scientific
Who is Quicksilver Scientific?
Quicksilver Scientific is a supplement company based in Louisville, Colorado. It was founded by Christopher Shade, PhD, whose background is in environmental science rather than marketing. Dr. Shade earned his PhD in Environmental Science and Aquatic Chemistry from the University of Illinois at Urbana-Champaign in 2005, and his research has focused on the chemistry of mercury and how it interacts with sulfur compounds, particularly glutathione (Quicksilver Scientific).
That background explains the company’s name, since quicksilver is an old name for mercury, and its early focus on detoxification and glutathione. Over time, the range has expanded into vitamins, minerals, cognitive support, omega-3s and more.
A few facts the company highlights on its website (Quicksilver Scientific):
- Made in the USA, in a facility with NSF GMP certification.
- In-house laboratories, including a PJLA-certified cGMP quality testing laboratory and a CLIA-certified clinical laboratory.
- 38 patents issued or pending.
- More than 30,000 healthcare practitioners and patients using its products, with sales in more than 30 countries.
Quicksilver sells to both healthcare practitioners and consumers. Many people first encounter the brand through a functional medicine doctor, naturopath or chiropractor, but anyone can buy directly from the website.
Why the detox and glutathione focus?
Dr. Shade’s research on mercury and its interaction with sulfur compounds, especially glutathione, shaped the company’s early direction (Quicksilver Scientific). Glutathione is part of the body’s own system for handling oxidative stress and supporting natural detoxification processes, so it’s no surprise that liposomal glutathione and detox-oriented systems became signature products. Today the range is much broader, but that research heritage is still visible in how the company describes and formulates its products.
What does “liposomal” actually mean?
This is the heart of Quicksilver’s approach, so it’s worth understanding properly.
A liposome is a tiny sphere made of phospholipids, the same kind of fat-based molecules that form the membranes around your cells. Phospholipids have a water-loving head and a fat-loving tail, so in water they naturally arrange themselves into bubble-like structures. Those structures can carry nutrients, either inside the watery core or within the fatty layer.
A nanoemulsion is a related idea: oil-based nutrients broken down into extremely small droplets that disperse evenly in liquid. Quicksilver uses the term for several products, such as its D3K2, which is fat-soluble.
Why go to all this trouble? Some nutrients are difficult for the body to absorb in conventional form. They may be broken down in the digestive tract, or, like many fat-soluble vitamins, they may need fat to be absorbed well. The idea behind liposomal and nanoemulsion delivery is to package nutrients in a form the body can take up more easily.
What the evidence says
Liposomal delivery is a real, well-established technology. It’s used in pharmaceuticals, and research has explored liposomal forms of nutrients such as vitamin C and glutathione. Some studies suggest that liposomal forms can raise blood levels of certain nutrients more effectively than standard forms.
That said, a few honest caveats apply:
- Results vary by nutrient. Evidence for one liposomal nutrient doesn’t automatically apply to another.
- Results vary by product. How a liposome is made, its size and its stability all matter, so not every liposomal product performs the same.
- Better absorption isn’t the same as a health outcome. Higher blood levels of a nutrient don’t by themselves guarantee a specific benefit.
Quicksilver describes its products as “highly bioavailable” and designed for “high absorption.” Those are the company’s claims. If you’re choosing between products, it’s reasonable to see liposomal delivery as a meaningful feature, while keeping realistic expectations.
How to take Quicksilver Scientific supplements
Quicksilver’s liquid supplements are taken a little differently from capsules. The directions on the product pages follow a consistent pattern (Liposomal Glutathione, D3K2):
- Pump the dose into your mouth. Each pump delivers a measured amount. Check the label for the number of pumps per serving.
- Hold it in your mouth for 30 to 90 seconds. Many products are designed to be held under the tongue or in the mouth before swallowing.
- Swallow. Then go about your day.
- Take on an empty stomach. The directions recommend taking at least 10 minutes before meals.
- Store as directed. Some products, such as Liposomal Glutathione, ship with ice packs and should be refrigerated on arrival. Glutathione should be used within 30 days of opening and kept away from light.
The liquids are flavored, often with natural citrus and mint oils, to make holding them in your mouth more pleasant. Some contain a small amount of ethanol as part of the formula, which is worth knowing if you avoid alcohol entirely.
See Quicksilver’s best sellers
Three best sellers, up close
Quicksilver’s range is large, but three products show up again and again among its best sellers. Here’s what’s in each, based on the product pages in October 2026.
1. Liposomal Glutathione
Glutathione is an antioxidant your body makes on its own from three amino acids. It plays a role in neutralizing free radicals and in the body’s natural detoxification processes. Because it’s poorly absorbed in standard oral form, it’s one of the nutrients most often sold in liposomal form, and it’s closely tied to Dr. Shade’s research background.
- Size: 1.7 fl oz (50 mL), about 50 servings
- Per serving (1 mL, 2 pumps): 100 mg glutathione and 75 mg phosphatidylcholine from sunflower lecithin
- Flavors: lemon mint or cacao mint
- Directions: 2 to 4 pumps, held in the mouth 30 to 90 seconds, on an empty stomach
- Storage: refrigerate; use within 30 days of opening
- Price: $45
According to the product page, it may support antioxidant status, detoxification, energy production, immune function and healthy aging (Quicksilver Scientific). It’s vegan, sugar-free, tested gluten-free and allergen-free, and non-GMO.
2. D3K2
Vitamin D3 and vitamin K2 are often paired. Vitamin D supports calcium absorption, and vitamin K2 is involved in directing calcium to the right places in the body, such as bones. Both are fat-soluble, which is why a nanoemulsion format makes sense.
- Size: 1.7 fl oz (50 mL), about 100 servings
- Per serving (0.5 mL, 1 pump): 2,500 IU (62.5 mcg) vitamin D3 as cholecalciferol and 90 mcg vitamin K2 as menaquinone-7 (MK-7)
- Directions: 1 pump, 1 to 2 times daily, held in the mouth 30 to 90 seconds, on an empty stomach
- Price: $55
The product page lists bone and muscle support, immune function, mood support and cardiometabolic health among its intended uses (Quicksilver Scientific). One important safety note: vitamin K can interact with blood-thinning medications such as warfarin. If you take any anticoagulant, speak with your doctor before using a product that contains vitamin K.
3. Methyl B-Complex
B vitamins are involved in energy metabolism, nervous system function and many other processes. Quicksilver’s Methyl B-Complex is a liposomal liquid with a full range of B vitamins.
- Size: 1.7 fl oz (50 mL), about 50 servings
- Per serving (1 mL, 2 pumps): includes 500 mcg vitamin B12 as methylcobalamin and folate as calcium folinate (850 mcg DFE), along with B1, B2, B3, B5, B6 and biotin
- Extras: phosphatidylcholine, milk thistle seed extract and trimethylglycine (betaine)
- Flavor: lemon raspberry
- Price: $50
An interesting detail: despite the “Methyl” name, the folate is provided as folinic acid rather than methylfolate. The company’s FAQ says this is a deliberate choice to avoid over-methylation (Quicksilver Scientific). That kind of formulation reasoning is typical of the brand’s practitioner-focused approach.
The three at a glance
| Product | Bottle | Servings | Key amount per serving | Price | Approx. cost per serving |
|---|---|---|---|---|---|
| Liposomal Glutathione | 50 mL | 50 | 100 mg glutathione | $45 | $0.90 |
| D3K2 | 50 mL | 100 | 2,500 IU D3 + 90 mcg K2 | $55 | $0.55 |
| Methyl B-Complex | 50 mL | 50 | 500 mcg B12 + full B range | $50 | $1.00 |
Cost per serving is the list price divided by the servings per bottle, before any subscription discount. Your actual cost depends on how many pumps you take.
Other products worth knowing
Beyond the three best sellers, Quicksilver’s catalog includes:
- Liver Sauce ($73 for 100 mL), a liquid formula aimed at liver support.
- PushCatch Liver Detox (listed at $133 on sale from $141.50 at the time of writing), a two-part system that reflects the company’s detox roots.
- Protocols and bundles, which group products for specific goals and can work out better value than buying items individually.
- Quinton marine products, mineral-rich formulas derived from seawater. Quicksilver’s website references Informed Sport certification for this line, which may matter to competitive athletes.
- Cognitive support, omega-3 fish oil and magnesium products, including magnesium L-threonate.
Some products, especially detox systems, are designed to be used under the guidance of a healthcare practitioner. If you’re considering a multi-step protocol, it’s a good idea to involve a professional who knows your health history.
Quality and testing
Supplements in the US aren’t approved by the FDA before they go on sale, so quality can vary a lot between brands. That makes a company’s manufacturing and testing standards especially important.
Quicksilver emphasizes several quality markers on its website: products are made in the USA in an NSF GMP-certified facility, the company runs a PJLA-certified cGMP quality testing laboratory and a CLIA-certified clinical laboratory, and products are labeled as tested allergen-free and, in many cases, tested gluten-free, non-GMO and soy protein-free (Quicksilver Scientific).
Certifications like these don’t prove a product will work for you, but they do indicate a company that invests in consistent manufacturing and testing. That’s a meaningful signal in an industry where quality control varies widely.
Buy from the source or authorized sellers
Popular supplement brands are sometimes sold by unauthorized third-party sellers, where storage conditions and authenticity are harder to verify. This matters even more for liposomal products, some of which should be refrigerated. Quicksilver’s satisfaction guarantee only covers purchases from its own website or authorized sellers, which is another reason to buy directly.
Shop direct from Quicksilver Scientific
How to read a supplement label
Whether you buy Quicksilver or another brand, knowing how to read a label helps you compare products and avoid surprises. Here’s what to look for:
- Serving size. For liquids, this is usually expressed in milliliters and pumps. Quicksilver’s Glutathione and Methyl B-Complex use 1 mL (2 pumps) per serving, while D3K2 uses 0.5 mL (1 pump). The amounts listed apply to one serving, not one pump.
- Amount per serving and % Daily Value. The Daily Value shows how a serving compares with general reference amounts. D3K2’s 2,500 IU of vitamin D3 is listed at 313% of the Daily Value, for example. Some nutrients, like vitamin K2 or glutathione, don’t have an established Daily Value.
- The form of each nutrient. Forms matter. “Vitamin K2 as menaquinone-7” and “B12 as methylcobalamin” tell you more than “vitamin K” or “B12” alone.
- Other ingredients. This is where you’ll find carriers, flavors and preservatives, such as glycerin, natural flavor oils or ethanol. Check here if you have sensitivities.
- Certifications and testing claims. Look for third-party certifications such as NSF GMP, and for testing claims like “tested gluten-free.”
- Directions and warnings. Read these closely. They tell you when and how to take the product, how to store it, and who should talk to a doctor first.
- The FDA disclaimer. You’ll see a statement that claims haven’t been evaluated by the FDA. This appears on supplements generally and is a reminder that supplements aren’t approved like medicines.
Pricing and ways to save
Quicksilver Scientific is a premium brand. Most of its single liquid supplements sit in the $45 to $75 range per bottle, and systems and protocols cost more. Here’s how to keep costs reasonable:
- Subscribe & Save. Subscriptions save 10% on every monthly order, not just the first. You can change your next shipping date, suspend, add or remove products, or cancel from your account (Subscribe & Save). Monthly is currently the only frequency.
- Reach free shipping. Consumer orders over $99 ship free within the continental US.
- Consider bundles and protocols. If you’ll use several products together, a bundle can be better value.
- Calculate cost per serving. A product with more servings per bottle, like D3K2, can be cheaper per day than its price suggests.
- Use only what you need. Work with your healthcare provider on the right dose rather than defaulting to the maximum suggested amount.
Shipping, returns and the guarantee
Here’s a summary of the key policies, based on Quicksilver’s shipping and returns page in October 2026 (Shipping policy). Policies can change, so check before you order.
| Policy | What you need to know |
|---|---|
| Free shipping | Consumer orders over $99 (continental US) |
| Processing | Up to 3 business days before shipping |
| Delivery time | Standard typically 3 to 7 business days; expedited typically 2 to 3 |
| International | Canada, UK and EU via expedited service; duties and taxes collected at checkout; no returns or changes |
| Cold products | Refrigerated items are stable at room temperature for 5 to 7 days, so arriving warm doesn’t mean damaged |
| Returns | New, unused products within 30 days of receipt; customer pays return shipping; cold products not eligible |
| Satisfaction guarantee | 45 days for US purchases from the website or authorized sellers; refrigerated products and international orders excluded |
| Damaged or incorrect items | Report within 10 days with photos |
| Order changes | Orders can’t be changed or canceled once submitted |
Two practical notes. First, double-check your cart before you submit, since orders can’t be modified afterwards. Second, Quicksilver doesn’t ship to PO boxes, so use a street address.
Common mistakes when buying supplements online
- Buying from unverified sellers. Marketplace listings can be hard to verify, and products that need refrigeration may not have been stored properly. Buy from the brand or an authorized seller.
- Stacking too many products at once. Starting several supplements together makes it hard to know what’s helping, and increases the chance of doubling up on the same nutrient.
- Ignoring overlap. If you already take a multivitamin, check whether a new product repeats the same nutrients. Fat-soluble vitamins, such as vitamin D, can build up in the body, so more isn’t always better.
- Skipping the label directions. Timing, storage and dose instructions are there for a reason. For Quicksilver’s liquids, that means an empty stomach, the 30 to 90 second hold and, where relevant, refrigeration.
- Expecting overnight results. Supplements aren’t medicines, and any effects tend to be gradual. Give a product a fair trial and check in with your provider.
- Forgetting about returns. Refrigerated products often can’t be returned. Be confident before you order cold items.
The pros and cons
| What we like | What to consider |
|---|---|
| Specialist in liposomal and nanoemulsion delivery | Premium pricing compared with standard capsules |
| Founded by a PhD scientist with a research background | Absorption benefits vary by nutrient; evidence isn’t uniform |
| Made in the USA in an NSF GMP-certified facility, with in-house testing labs | Some products need refrigeration and should be used within 30 days of opening |
| Thoughtful formulations, such as folinic acid in the B-complex | Holding liquid in your mouth for up to 90 seconds takes getting used to |
| Subscribe & Save at 10% on every monthly order | Some formulas contain a small amount of ethanol |
| 45-day satisfaction guarantee on eligible US purchases | Refrigerated products and international orders are excluded from returns and the guarantee |
Who Quicksilver Scientific is best for
Quicksilver may be a good fit if you:
- Work with a functional or integrative medicine practitioner who recommends specific products or protocols.
- Struggle with capsules and prefer liquid supplements.
- Want liposomal forms of nutrients that are known to be harder to absorb in standard form.
- Care about manufacturing and testing standards and are willing to pay more for them.
- Like research-driven formulations and want to understand why ingredients were chosen.
Who should be cautious
- Anyone pregnant, breastfeeding or planning pregnancy, as the product labels advise consulting a physician first.
- People taking medications, especially blood thinners, which can interact with vitamin K.
- People with health conditions, who should involve their healthcare provider before adding supplements.
- Anyone avoiding alcohol entirely, since some formulas contain ethanol.
- Budget-focused shoppers, for whom a standard-form supplement may be a more affordable starting point.
What a simple routine can look like
Here’s an example of how someone might fit liquid supplements into a morning. It’s an illustration only; your own routine should be based on your provider’s advice.
- Wake up and have a glass of water.
- Take your first supplement. Pump the dose into your mouth, hold it for 30 to 90 seconds, then swallow.
- Take any others the same way. If you take more than one, many people take them one after another.
- Wait at least 10 minutes before breakfast. Use the time to shower, make coffee or check the weather.
- Put refrigerated bottles back in the fridge straight away.
Keeping your bottles in one spot, such as a shelf in the fridge door, makes the routine easy to remember.
Questions to ask your healthcare provider
If you’re considering Quicksilver products, or any supplement, these questions are worth bringing to your next appointment:
- Do I actually need this nutrient, and how would we know?
- Is there a lab test that would help, such as a vitamin D level?
- What dose makes sense for me, and for how long?
- Could this interact with any of my medications or conditions?
- How will we know if it’s helping?
- Is a liposomal form worth the extra cost for this particular nutrient?
Practitioners who work with Quicksilver products often have experience with them, which can make these conversations more productive.
Tips for getting started
- Talk to your healthcare provider. Ideally, base supplement choices on your health history and, where relevant, lab results. A provider can also help you avoid taking more than you need.
- Start with one product. Adding one supplement at a time makes it easier to notice how you feel and to spot any issues.
- Build a routine. Because these products are taken on an empty stomach, many people take them first thing in the morning, before breakfast.
- Keep refrigerated products cold. Put them in the fridge as soon as they arrive, and note the 30-day window after opening where it applies.
- Check the dose per pump. Different products deliver different amounts per pump, so read each label.
- Set up Subscribe & Save once you know what works. It’s a simple way to save 10% on products you use every month.
Liposomal vs. standard supplements: a quick comparison
| Feature | Standard capsules or tablets | Liposomal or nanoemulsion liquids |
|---|---|---|
| Format | Swallowed whole | Pumped into the mouth, held, then swallowed |
| Absorption | Varies; some nutrients absorb poorly | Designed to improve absorption; evidence varies by nutrient |
| Dose flexibility | Fixed per capsule | Easy to adjust by number of pumps |
| Storage | Usually shelf-stable | Some need refrigeration and have a use-by window after opening |
| Price | Generally lower | Generally higher |
| Best for | Budget, convenience, travel | People who prefer liquids or want liposomal forms |
Frequently asked questions
Who owns Quicksilver Scientific?
Quicksilver Scientific was founded by Christopher Shade, PhD, and is based in Louisville, Colorado.
Are Quicksilver Scientific products made in the USA?
Yes. The company says its products are made in the USA in an NSF GMP-certified facility.
Why do I hold the liquid in my mouth?
The directions call for holding the dose in your mouth for 30 to 90 seconds before swallowing. This is part of how the company designs its liquid products to be taken.
Do I need to refrigerate Quicksilver products?
Some, yes. Liposomal Glutathione, for example, ships with ice packs and should be refrigerated on arrival. Check each product’s label.
Is liposomal glutathione better than regular glutathione?
Standard oral glutathione is generally considered poorly absorbed, which is why liposomal forms are popular. Some research supports better absorption with liposomal forms, but results vary between studies and products.
Does Quicksilver offer a subscription discount?
Yes. Subscribe & Save offers 10% off every monthly order, and you can change dates, suspend or cancel from your account.
What’s the return policy?
New, unused products can be returned within 30 days of receipt, with the customer paying return shipping. Cold products and international orders aren’t eligible. There’s also a 45-day satisfaction guarantee for eligible US purchases.
Can I take Quicksilver supplements with medications?
Talk to your doctor or pharmacist first. Some ingredients, such as vitamin K, can interact with medications like blood thinners.
How long does a bottle last?
It depends on the product and your dose. At the suggested serving, a 50 mL bottle of Liposomal Glutathione or Methyl B-Complex lasts about 50 days, and D3K2 lasts about 100 days at one pump a day. Note that Glutathione should be used within 30 days of opening.
Does Quicksilver ship internationally?
Yes, to Canada, the UK and the EU for consumer orders, with duties and taxes collected at checkout. International orders can’t be returned or changed once placed.
The bottom line
Quicksilver Scientific stands out in a crowded supplement market for its focus on delivery technology, its science-led founder, and its investment in manufacturing and testing. Its liposomal and nanoemulsion liquids are a practical option for people who prefer liquids, want liposomal forms of hard-to-absorb nutrients, or work with a practitioner who recommends the brand.
It isn’t the cheapest option, and the benefits of liposomal delivery vary by nutrient, so keep your expectations grounded. But if quality, formulation and delivery matter to you, Quicksilver is a well-regarded brand worth considering. Talk to your healthcare provider about what you actually need, start with one product, and use Subscribe & Save once you’ve found what works for you.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
